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Artículos 2010

F. Cuenú, R. Abonia, J. Cobo, C. Glidewell, 1-(2-Aminophenyl)-3-(4-pyridyl)prop-2-en-1-one: a three-dimensional framework structure built from N-H...N, C-H...O and C-H...(arene) hydrogen bonds – Acta Cryst., C66, 589-592.



J. Trilleras, L. G. López, D. J. Pacheco, J. Quiroga, M. Nogueras, J. M. de La Torre, J. Cobo, Efficient Microwave-Assisted Synthesis of 5-Deazaflavin Derivatives – Molecules, 15, 7227-7234. 



J. Quiroga, P. A. Acosta, S. Cruz, R. Abonía, B. Insuasty, M. Nogueras, J. Cobo, Generation of Pyrrolo[2,3-d]pyrimidines. Unexpected Products in the Multicomponent Reaction of 6-Aminopyrimidines, Dimedone and Arylglyoxal – Tetrahedron Lett., 51, 5443-5447. 

Y. Díaz, J. Quiroga, J. Cobo, C. Glidewell, Two similarly substituted benzo[h]pyrazolo[3,4-b]quinoline-5,6(10H)-diones: supramolecular structures in two and three dimensions - Acta Cryst., C66, 305-309. 


J. Gálvez, J. Quiroga, J. Cobo, C. Glidewell, 2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)acetamide: complex sheets built from N-H…O and C-H…O hydrogen bonds – Acta Cryst., C66, 521-523. 


J. Quiroga, J. Trilleras, D. Pantoja, R. Abonía, B. Insuasty, M. Nogueras, J. Cobo, Microwave-Assisted Synthesis of Pyrazolo[3,4-b]pyridine-Spirocycloalkanediones by Three-Component Reaction of 5-Aminopyrazole Derivatives, Paraformaldehyde and Cyclic β-Diketones - Tetrahedron Lett., 51, 4717-4719. 


B. Insuasty, A. Tigreros, F. Orozco, J. Quiroga, R. Abonia, M. Nogueras, A. Sánchez, J. Cobo, Synthesis of Novel Pyrazolic Analogues of Chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole Derivatives as Potential Antitumor Agents - Bioorg. Med. Chem., 18, 4965-4974.


D. Becerra, B. Insuasty, J. Cobo, C. Glidewell, (9E)-9-Benzylidene-3-methyl-2-methylsulfanyl-5-phenyl-5,6,7,8,9,10-hexahydropyrimido[4,5-b]quinolin-4(3H)-one: polarized molecules within hydrogen-bonded bilayers - Acta Cryst., C66, 389-391.


B. Insuasty, A. García, J. Quiroga, R. Abonia, M. Nogueras, J. Cobo, Synthesis of novel 6,6a,7,8-tetrahydro-5H-naphtho[1,2-e]pyrimido[4,5-b][1,4]diazepines under microwave irradiation as potential anti-tumor agents - Eur. J. Med. Chem., 45, 2841-2846. 

J. Quiroga, Y. Diaz, B. Insuasty, R. Abonia, M. Nogueras, J. Cobo, Preparation of 6-chloropyrazolo[3,4-b]pyridine-5-carbaldehydes by Vilsmeier-Haack reaction and its use in the synthesis of heterocyclic chalcones and dipyrazolopyridines – Tetrahedron Lett., 51, 2928-2930.


J. Quiroga, J. Trilleras, M. B. Hursthouse, J. Cobo, C. Glidewell, (E)-N2-{4-[(E)-2-(4-Chlorobenzoyl)ethenyl]-3-methyl-1-phenyl-1H-pyrazol-5-yl}-N1,N1dimethylformamidine: polarized molecules within sheets of p-stacked hydrogen-bonded chains - Acta Cryst., C66, 245-248. 


B. Insuasty, A. García, R. Abonia, M. Nogueras, J. Cobo, 1,3,5-Tris-(2,3-dihydro-1H-1,5-benzodiazepin-4-yl)-1,2,3,4,5,6-hexahydro-s-triazine - Molbank, M664.

G. López, L. M. Jaramillo, R. Abonia, J. Cobo, C. Glidewell, Hydrogen-bonding patterns in three substituted N-benzyl-N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)acetamides - Acta Cryst., C66, 168-173. 


J. Quiroga, J. Trilleras, M. B. Hursthouse, J. Cobo, C. Glidewell, A hydrogen-bonded dimer in 6-(4-bromophenyl)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridine and a chain of rings built from N-H...N and C-H...pi(pyridine) hydrogen bonds in 3-(4-nitrophenyl)-4-phenyl-1H-pyrazolo[3,4-b]pyridine - Acta Cryst., C66, 163-167.


J. Quiroga, J. Portilla, M. B. Hursthouse, J. Cobo, C. Glidewell, 5-Amino-1-benzoyl-3-methylpyrazole: complex sheets built from N-H...N, C-H...O and C-H...pi(arene) hydrogen bonds - Acta Cryst., C66, 159-162.

J. Quiroga, J. Trilleras, B. Insuasty, R. Abonia, M. Nogueras, A. Marchal, J. Cobo, A Straightforward Synthesis of Pyrimido[4,5-b]quinoline Derivatives Assisted by Microwave Irradiation – Tetrahedron Lett., 51, 1107-1109.


J. Quiroga, J. Portilla, J. Cobo, C. Glidewell, A simple hydrogen-bonded chain in (3Z)-3-{1-[(5-phenyl-1H-pyrazol-3-yl)amino]ethylidene}-4,5-dihydrofuran-2(3H)-one, and a hydrogen-bonded ribbon of centrosymmetric rings in the self-assembled adduct (3Z)-3-{1-[(5-methyl-1H-pyrazol-3-yl)amino]ethylidene}-4,5-dihydrofuran-2(3H)-one-6-(2-hydroxy-ethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one (1/1) - Acta Cryst., C66, 25-28. 


R. Abonía, P. Cuervo, M. B. Hursthouse, J. Cobo, C. Glidewell, 1-(6-Amino-1,3-benzodioxol-5-yl)-3-(2-oxo-1,2-dihydroquinolin-3-yl)prop-2-enone: a sheet built by -stacking of hydrogen-bonded chains of rings - Acta Cryst., C66, 44-46. 


J. C. Castillo, R. Abonía, M. B. Hursthouse, J. Cobo, C. Glidewell, N-(3-tert-Butyl-1-phenyl-1H-pyrazol-5-yl)-N-(4-methoxybenzyl)acetamide: a hydrogen-bonded chain of centrosymmetric rings - Acta Cryst., C66, 64-66.


J. Quiroga, J. Trilleras, J. Cobo, C. Glidewell, 2-Amino-4-(piperidin-1-yl)-11H-pyrimido[4,5-b][1,5]benzodiazepin-6-ium chloride monohydrate and 2-amino-4-[methyl(2-methylphenyl)amino]-11H-pyrimido[4,5-b][1,5]benzodiazepin-6-ium chloride-benzene-1,2-diamine (1/1): complex sheets generated by multiple hydrogen bonds - Acta Cryst., C66, 154-158.


Y. Díaz, J. Quiroga, J. Cobo, C. Glidewell, (E)-N-{[6-Chloro-4-(4-chlorophenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl]methylene}benzene-1,2-diamine: a three-dimensional framework structure built from only two hydrogen bonds - Acta CrystC66, 137-140. 


D. Becerra, B. Insuasty, J. Cobo, C. Glidewell, Hydrogen-bonding patterns in 3-alkyl-3-hydroxyindolin-2-ones - Acta Cryst. C66, 79-86.  


J. C. Castillo, R. Abonía, M. B. Hursthouse, J. Cobo, C. Glidewell, N-(3-tert-Butyl-1-phenyl-1H-pyrazol-5-yl)-N-(4-methoxybenzyl)acetamide: a hydrogen-bonded chain of centrosymmetric rings - Acta Cryst., C66, 64-66  (2010).


R. Abonia, P. Cuervo, J. C. Castillo, B. Insuasty, J. Quiroga, M. Montiel, J. Cobo, A simple one-pot synthesis of new imidazo-2-yl-1H-quinolin-2-ones from the direct reaction of 2-chloroquinolin-3-carbaldehyde with aromatic o-diamines – Eur. J. Org. Chem2010, 317-325.


B. Insuasty, A. Gutiérrez, J. Quiroga, R. Abonia, M. Nogueras, J. Cobo, L. Svetaz, M. Raimondi, S. Zacchino, Fungicide activity of 5-(4-chlorobenzylidene)-(Z)-2-dimethylamino-1,3-thiazol-4-one against Cryptococcus neoformans – Archiv Pharm343, 48-53. 


J. Quiroga, J. Trilleras, J. Cobo, C. Glidewell, 5-Amino-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde hemihydrate: a polarized electronic structure within hydrogen-bonded sheets of R108(34) rings - Acta Cryst.C66, 47-49.


J. Quiroga, J. Gálvez, M. B. Hursthouse, J. Cobo, C. Glidewell, 2-Cyano-N-(2,6-dimethoxypyrimidin-4-yl)-3-[4-(dimethylamino)phenyl]acrylamide and dimethylammonium 6-cyano-1,3-dimethyl-2,4,5-trioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidin-8-ide: a pi-stacked dimer and a hydrogen-bonded ribbon containing three types of ring - Acta Cryst.C66, 39-43. 


R. Abonia, J. C. Castillo, B. Insuasty, J. Quiroga, M. Nogueras, J. Cobo, An Efficient Synthesis of 7-(Arylmethyl)-3-tert-butyl-1-phenyl-6,7-dihydro-1H,4H-pyrazolo[3,4-d][1,3]oxazines – Eur. J. Org. Chem.2010, 6454-6463. 


J. C. Castillo, R. Abonía, J. Cobo, C. Glidewell, Pseudomerohedral twinning, pseudosymmetry and complex hydrogen-bonded sheets in 2-methoxy-4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenol - Acta Cryst., C66, 385-388. 


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